Vaping refers to the act of inhaling and exhaling aerosol, often called vapor, produced by an electronic cigarette or similar device. These devices heat a liquid that usually contains nicotine, flavorings, and Vaping For Beginners: How Do You Inhale and Exhale Vapor? Medical Marijuana, Inc. Smoking vs. Vaping: Is One Really Safer Than the Other? If you vape, you inhale a lot of harmful substances. These can damage your heart and lungs.