Emerging role of trimethylamine N oxide (TMAO) in colorectal cancer Applied Microbiology and Biotechnology Springer Nature Link Trimethylamine N oxide (TMAO) is a small molecule produced in humans primarily by the gut liver axis and has become an important biomarker, and possible mediator, of cardiometabolic and renal disease. Dietary choline, phosphatidylcholine ( Gut Microbiome Derived Metabolite Trimethylamine N Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans Hypertension Frontiers Effects of choline metabolitetrimethylamine N oxide on immunometabolism in inflammatory bowel disease