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glutathione depletion paracetamol Pyroglutamic acidosis
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Paracetamol Induced Hepatotoxicity , Overdose NAPQI formation Glutathione depletion Liver cell necrosis. Early N acetylcysteine (NAC) can save the liver., #Pharmacology #mbbs #Hepatotoxicity Refractory high anion gap metabolic acidosis due to chronic paracetamol use: a case report Journal of Medical Case Reports Springer Nature Link Sulfate conjugation may be the key to hepatotoxicity in paracetamol overdose Li 2021 British Journal of Clinical Pharmacology Wiley Online Library Acetaminophen or Tylenol Toxicity Lect 19 Pharmacology
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glutathione depletion paracetamol Pyroglutamic acidosis
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