Clinical Challenge: Dark Lesion on Lower Lip MPR Removal of lip pigmentation with our Alma Q laser. Such lip spots (aka labial melanotic macules) appear for no apparent reason. Similar spots can appear due to smoking, sun damage, drug reactions, Spot the Dot! Growths on the lips are not too common. Clinically, this was consistent with a labial melanotic macule (aka freckle on the lip). These are benign growths which can be Dermoscopy of venous lake on the lips: A comparative study with labial melanotic macule PLOS One
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melanotic macule of lip Labial Lentigo (labial melanotic macule)