Metabolism: The pentose phosphate pathway and G6PD deficiency (practice) Khan Academy G6PD Deficiency Glucose 6 phosphate dehydrogenase deficiency X linked recessive disorder Leads to low NADPH, impairing glutathione regeneration RBCs are vulnerable to oxidative damage Pathophysiology: In G6PD deficiency: No Glucose 6 Phosphate Dehydrogenase Deficiency and Cardiovascular Risk in Familial Hypercholesterolemia: A Retrospective Cohort Study Glucose 6 phosphate Dehydrogenase (G6PD) Enzyme ROS Scavenger Biochemistry & Hematology