GHK Cu is a naturally occurring tripeptide in human plasma. Levels average 200 ng ml at age 20 and drop to 80 ng ml by age 60 (Pickart et al., 2020). That decline tracks with Defy GHK Cu (glycyl L histidyl L lysine) is a naturally occurring copper binding peptide found in human plasma. As levels decline with age, so may its support of the biological processes involved in collagen production, skin Copper peptides like GHK Cu work by sending signals to your skin to repair, regenerate, and produce collagen. It's not about instant results, it's about improving how your skin functions over time. Dr. Proposed acidic degradation pathway of GHKCu in acidic solution. Download Scientific Diagram