BPC 157 in Australia: Benefits, side effects, risks and legality Most people who talk about side effects from BPC 157 dont realize the problem isnt the peptide itself. The issue is that theyre getting unsterile, contaminated products from low quality research Orthopedic Use of BPC 157 Sports Med Review Peptide side effects no one talks about BPC 157 headaches. TB 500 fatigue. CJC Ipamorelin water retention. Most people quit. But 90% of the time it's the protocol, not the peptide.