Association between acetaminophen metabolites and CYP2E1 DNA methylation level in neonate cord blood in the Boston Birth Cohort Clinical Epigenetics Springer Nature Link Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: AQUA SKIN is a Japanese brand focusing on improving beauty and wellness. With continuous research and development, we came up with premium products to help improve skin and health housing Japan's finest Can Tylenol (acetaminophen) deplete glutathione levels in the body?