Are Peptides coming off of the FDA Category 2 list? A legal breakdown. The FDA just changed the rules on peptides effective April 15, 2026. BPC 157, GHK Cu, MOTS C, and TB 500 have been removed from the Category 2 restricted compounding list. Here is what The Sikiric Problem: One Lab, Thirty Years, Zero Trials That Matter FDA has removed certain bulk drug substances that were placed on the category two list and has announced it will consult the Pharmacy Compounding Advisory Committee (PCAC) for potential future inclusion of