If you're battling kidney disease, you already know this: your kidneys won't heal by accident. You need a system. You need tools. You need guidance. But most importantly, you need the right WhyScience #Day33: Genome wide studies have uncovered >1,000 loci linked to kidney function, but pinpointing causal genes remains a hurdle. In our new @SciTransMed paper, we integrated human multi omics and mouse models to Bioactivation of the Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor Atabecestat Leads to Protein Adduct Formation on Glutathione S Transferase Pi Chemical Research in Toxicology Glutathione specific gammaglutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis Science Translational Medicine