Glutathione is one of the most important molecules in detoxification. It drives Phase II conjugation and helps neutralize oxidative stress at the cellular level. But detoxification does not end with transformation. It Disruption in glutathione metabolism and altered energy production in the liver and kidney after ischemic acute kidney injury in mice Scientific Reports Most kidney patients are focused on creatinine while almost nobody is talking about what's happening inside the kidney cells. That's where NAC and ALA become interesting. Because kidney disease is not just Acute kidney injury model established by systemic glutathione depletion in mice Matsubara 2019 Journal of Applied Toxicology Wiley Online Library