Glutathione is a powerful antioxidant often marketed for brighter, more even skin tone and reduction of dark spots from acne or sun damage. While oral glutathione may offer mild skin brightening Glutathione Injection Cost, Benefits, Side Effects Effect of an Oral Formulation on Skin Lightening: Results from In Vitro Tyrosinase Inhibition to a Double Blind Randomized Placebo Controlled Clinical Study in Healthy Asian Participants Intravenous glutathione for skin lightening: Inadequate safety data