Oral Melanotic Macule MEDizzy An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic Oral pigmented lesions: a pragmatic approach to diagnosis and management Faculty Dental Journal Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor