N acetylcysteine (NAC) is an antioxidant and anti inflammatory compound that helps the body reduce oxidative stress by boosting levels of glutathione, one of the body's main natural defenses against inflammation. In a study Picture your detox system as a busy highway. Randee Fagen Glutathione: A small molecule with big sense How do glutathione and Nacetylcysteine (NAC) compare regarding indications, dosing, effectiveness, and safety for acetaminophen toxicity, mucolytic therapy, and general antioxidant supplementation?