Exploring the Evidence of N Acetyl Cysteine (NAC) for Mood Disorders Psychopharmacology Institute The distance between a compound demonstrating efficacy in preclinical research and that compound appearing in a physician's standard toolkit can span a generation. The mechanisms by which NAC addresses oxidative stress, glutamate Why Glutathione Matters: The Link Between Detoxification and Chronic Disease Wholehealthweb PDF) Prefrontal cortex glutathione S transferase levels in patients with bipolar disorder, major depression and schizophrenia