Dosedependent pharmacokinetics of acetaminophen: Evidence of glutathione depletion in humans Slattery 1987 Clinical Pharmacology & Therapeutics Wiley Online Library What will happen to the liver of a patient with fatty liver disease (steatosis) given 4 grams of acetaminophen (paracetamol) per day for 4 weeks? Glutathione and Oxidative Stress The Case Severe high anion gap metabolic acidosis Kidney International
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glutathione depletion acetaminophen ACETAMINOPHEN-INDUCED HEPATIC NECROSIS. IV. PROTECTIVE ROLE OF GLUTATHIONE