Glucose 6 phosphate dehydrogenase deficiency Knowledge @ AMBOSS Figure, Glucose 6 Phosphate Dehydrogenase (G6PD) Deficiency. Diagram] StatPearls NCBI Bookshelf Frontiers Recent findings in the regulation of G6PD and its role in diseases G6PD Deficiency Glucose 6 phosphate dehydrogenase deficiency X linked recessive disorder Leads to low NADPH, impairing glutathione regeneration RBCs are vulnerable to oxidative damage Pathophysiology: In G6PD deficiency: No