Glycine, the smallest amino acid in nature, interacts with NMDA receptors in the brain's sleep regulating center and may help support sleep onset. Human trials found that 3 grams of glycine before bedtime Glycine is becoming ever more popular as a sleep supplement. Most people assume it works like magnesium or melatonin, some vague calming effect. It doesn't. The mechanism is specific, well mapped, and has The Dual Role of Astrocytes in CNS Homeostasis and Dysfunction Which one of these supplements is making me so sleepy? : r Biohackers