What Peptides Are Legal in the U.S.? Understanding FDA Approval, Compounding, and the Legal Gray Areas Holt Law FDA to weigh easing limits on unproven peptides favored by RFK Jr. and other MAHA figures Pittsburgh Post Gazette In a major policy shift, the U.S. Food and Drug Administration is reconsidering restrictions on several controversial peptides, including trending compounds like BPC 157 and Melanotan II. The move comes as demand for The trend of unproven peptides is spreading through influencers and RFK Jr. allies CNN