Ipamorelin and CJC 1295 are almost always discussed together in research circles, and the reason comes down to receptor pharmacology. The two peptides work through entirely different but complementary mechanisms that produce a LEAP2 Is an Endogenous Antagonist of the Ghrelin Receptor: Cell Metabolism Ipamorelin Supra Chems Table 3 from Ipamorelin, the first selective growth hormone secretagogue. Semantic Scholar