Full article: An increase of oxidative stress markers and the alteration of the antioxidant enzymatic system are associated with spleen damage caused by methimazole induced hypothyroidism How to Increase Glutathione to Protect Against Hashimoto's This one antioxidant is ULTRA important for your thyroid function Glutathione is our body's master antioxidant meaning it's the most important and abundant one. As it relates to the thyroid, think Propylthiouracil induced congenital hypothyroidism upregulates vimentin phosphorylation and depletes antioxidant defenses in immature rat testis in: Journal of Molecular Endocrinology Volume 40 Issue 3 (2008)