Methimazole induced hypothyroidism causes alteration of the REDOX environment, oxidative stress, and hepatic damage; events not caused by hypothyroidism itself Annals of Hepatology Glutathione is the body's primary internal antioxidant, made using the amino acid cysteine, and it helps protect cells from oxidative stress. Beyond detoxification, research shows glutathione is involved in thyroid hormone metabolism, Glutathione S Transferase pi 1 GSTP1 Antibody (OTI4B6) Azide and BSA Free Multiple nutritional factors and thyroid disease, with particular reference to autoimmune thyroid disease Proceedings of the Nutrition Society Cambridge Core