Vaping doubles risk of serious lung disease, even without smoking history study Professor Erwin Loh E cig use associated with asthma, COPD in never smokers Stanton Glantz blog Frontiers Inhalation of nicotine containing electronic cigarette vapor exacerbates the features of COPD by inducing ferroptosis in ENaC overexpressing mice A new study published in Nicotine & Tobacco Research found that those using e cigarettes alone were more than twice as likely to develop COPD than people who didn't use any tobacco products,